How Niacinamide works on Arthritis:
Niacinamide helps in reducing the pain and swelling of arthritis and it has been show to prevent the degeneration of join tissue. Niacinamide inhibits Nitric Oxide which is a cell-killing free radical that is associated with the breakdown of joint cartilage. Do not take niacin because it has a different biological effect on the body. Improvement on pain and swelling can be seen within twelve to sixteen weeks. Prolonged use of niacinamide helps in keeping improved joint flexibility. Another good effect of Niacinamide is that it improves depression.
Side Effects and Precautions of Niacinamide:
There has been no reported adverse side effects associated with niacinamide use.
Forms, Dosage and Brandnames:
Adults: It is recommended to take from 500 to 1000 milligrams of Niacinamide two to three times a day with Vitamin-C. There are lots of store brand niacinamide and generic brands on the market, look for niacinamide packed on thin gel capsules for better digestive track absorption. Dr. William Kaufman recommends as high as 4,000 mg per day (divided into three doses per day for 1 to 3 months) for patients who are severely crippled with arthritis.
Pregnant Women: Safe and well tolerated.
Children: Safe and well tolerated.
References about Niacinamide and Arthritis:
Niacinamide Silencing the Aging Gene: Another Look at Clinical Uses for the, By Daniel J. Bourassa, D.C.
Niacinamide therapy for joint mobility. Conn. State Med. J. 17:584-589, 1953 Niacinamide, a most neglected vitamin. 1978 Tom Spies Memorial Lecture. J. Int. Acad. of Preventive Med. 8:5-25,1983 Niacinamide improves mobility in degenerative joint disease. Abstract published in Program of the American Association for the Advancement of Science for its meeting in Philadelphia, May 24-30, 1986