How Chondroitin works on Arthritis:
Chondroitin
is necessary for the resiliency of the cartilage and is a
component of the cartilage itself. Studies show that Chondroitin
keeps the enzyme that causes the breakdown of cartilage at
lower levels and also helps fight inflammation. It also stimulates
the synthesis of cartilage tissues for healthier joints. It
is best to take Chondroitin with Glucosamine because they
work synergistically.
Side
Effects and Precautions of Chondroitin:
The
most common side effect is increased intestinal gas and soft
stools. It may cause bleeding in people who have bledding
disorder. Take
extra caution if you have diabetes or if you are allergic
to shellfish. Some cases of nausea and heartburn is reported.
Chondroitin may also cause bleeding in persons with bleeding
disorders.
Forms,
Dosage and Brand Names of Chondroitin:
Adults:
Chondroitin sulfate: 1200 mg daily taken as 400 mg capsules
or tablets three times a day. Glucosamine HCl dosage: 1500
mg daily taken as 500 mg capsules or tablets three times a
day.
Pregnant
Women: Consult your doctor before taking this medication
Children:
There is no proven effective dose in children.
References
about Chondroitin and Arthritis:
Reginster
JY, Gillot V, Bruyere O, Henrotin Y. Evidence of nutriceutical
effectiveness in the treatment of osteoarthritis. Curr Rheumatol
Rep 2000; 2: 472-77.
Constantz
RB. Hyaluronan, glucosamine and chondroitin sulfate: roles
for therapy in arthritis? In: Kelley WN, Harris ED, Ruddy
S, Sledge CB, eds. Textbook of rheumatology. Philadelphia:
WB Saunders, 1998.
Deal
CL, Moskowitz RW. Nutraceuticals as therapeutic agents in
osteoarthritis: the role of glucosamine, chondroitin sulfate,
and collagen hydrolysate. Rheum Dis Clin North Am 1999; 25:
379-95.
McAlindon
TE, LaValley MP, Gulin JP, Felson DT. Glucosamine and chondroitin
for treatment of osteoarthritis: a systematic quality assessment
and meta-analysis. JAMA 2000; 283: 1469-75.
Page last updated: May 02, 2008
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