How Chondroitin works on Arthritis:
Chondroitin is necessary for the resiliency of the cartilage and is a component of the cartilage itself. Studies show that Chondroitin keeps the enzyme that causes the breakdown of cartilage at lower levels and also helps fight inflammation. It also stimulates the synthesis of cartilage tissues for healthier joints. It is best to take Chondroitin with Glucosamine because they work synergistically.
Side Effects and Precautions of Chondroitin:
The most common side effect is increased intestinal gas and soft stools. It may cause bleeding in people who have bledding disorder. Take extra caution if you have diabetes or if you are allergic to shellfish. Some cases of nausea and heartburn is reported. Chondroitin may also cause bleeding in persons with bleeding disorders.
Forms, Dosage and Brand Names of Chondroitin:
Adults: Chondroitin sulfate: 1200 mg daily taken as 400 mg capsules or tablets three times a day. Glucosamine HCl dosage: 1500 mg daily taken as 500 mg capsules or tablets three times a day.
Pregnant Women: Consult your doctor before taking this medication.
Children: There is no proven effective dose in children.
References about Chondroitin and Arthritis:
Reginster JY, Gillot V, Bruyere O, Henrotin Y. Evidence of nutriceutical effectiveness in the treatment of osteoarthritis. Curr Rheumatol Rep 2000; 2: 472-77.
Constantz RB. Hyaluronan, glucosamine and chondroitin sulfate: roles for therapy in arthritis? In: Kelley WN, Harris ED, Ruddy S, Sledge CB, eds. Textbook of rheumatology. Philadelphia: WB Saunders, 1998.
Deal CL, Moskowitz RW. Nutraceuticals as therapeutic agents in osteoarthritis: the role of glucosamine, chondroitin sulfate, and collagen hydrolysate. Rheum Dis Clin North Am 1999; 25: 379-95.
McAlindon TE, LaValley MP, Gulin JP, Felson DT. Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysis. JAMA 2000; 283: 1469-75.